Relevance of NAT2 genotype to anti-tuberculosis drug-induced hepatotoxicity in a Chinese Han population.

Lihuan LuBilin TaoHaixu WeiHongbo ChenXiaomin HeHongqiu PanMiaomiao YangHonggang YiShao-Wen Tang

Published in: The journal of gene medicine (2019)

The present study is the first to validate the relationships between the tagging SNP rs1495741 and ATDH in a Chinese population. Based on this case-control study, the NAT2 rs1495741 polymorphism is a risk factor for mild but not more severe ATDH in Chinese Han patients.

Keyphrases

drug induced
liver injury
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
adverse drug
genome wide
emergency department
hiv aids
pulmonary tuberculosis
patient reported