Clinical and Biologic Characteristics and Outcomes in Young and Middle-Aged Patients With Laryngeal Cancer: A Retrospective Cohort Analysis.

Calvin X GengPriscilla TanamalSimone Arvisais-AnhaltMassimo TomasinoTarik GheitJustin A BishopDoreen N PalsgroveEllen WangJordan R SalleyKathleen M TibbettsBaran D SumerBrittny N TillmanAndrew T Day

Published in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2022)

Almost one-quarter of YMA patients lacked characteristic risk factors for laryngeal squamous cell carcinoma, and their tumors exhibited a higher prevalence of high-risk HPV. The significance of HPV16 and other tumor viruses with outcomes in nontraditional patients should be evaluated further.

Keyphrases

end stage renal disease
squamous cell carcinoma
middle aged
ejection fraction
newly diagnosed
chronic kidney disease
rheumatoid arthritis
peritoneal dialysis
high grade
risk factors
type diabetes
radiation therapy
metabolic syndrome
papillary thyroid
patient reported
genetic diversity