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Reappraisal of CSF-specific oligoclonal bands in Asia.

Ki Hoon KimSu-Hyun KimNa Young ParkJae-Won HyunHo Jin Kim
Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)
The prevalence of cerebrospinal fluid-specific oligoclonal bands (CSF-OCBs) was reported to be low in Asian people with multiple sclerosis (pwMS) compared to that in Western pwMS. It is yet to be determined whether it is a genuine feature of Asian pwMS or a misapprehension owing to past mis-classification of MS-mimicking diseases as MS. We aimed to reappraise the prevalence of CSF-OCBs in Korean pwMS after carefully excluding other central nervous system-inflammatory demyelinating diseases since 2017. Among 88 subjects, 78 (88.6%) were positive for CSF-OCBs, which suggests the prevalence of CSF-OCBs is not different between Korean and Western pwMS.
Keyphrases
  • cerebrospinal fluid
  • multiple sclerosis
  • risk factors
  • machine learning
  • mass spectrometry
  • deep learning
  • ms ms
  • south africa
  • oxidative stress
  • white matter