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Identification of NDM-1 in a Putatively Novel Acinetobacter Species ("NB14") Closely Related to Acinetobacter pittii.

Paula EspinalNoraida MosquedaMurat TelliTanny van der ReijdenDora RoloDietmar Fernández-OrthLenie DijkshoornIgnasi RocaJordi Vila
Published in: Antimicrobial agents and chemotherapy (2015)
In this study, we describe the molecular characterization of a plasmid-located blaNDM-1 harbored by an Acinetobacter clinical isolate recovered from a patient in Turkey that putatively constitutes a novel Acinetobacter species, as shown by its distinct ARDRA (amplified 16S ribosomal DNA restriction analysis) profile and molecular sequencing techniques. blaNDM-1 was carried by a conjugative plasmid widespread among non-baumannii Acinetobacter isolates, suggesting its potential for dissemination before reaching more clinically relevant Acinetobacter species.
Keyphrases
  • acinetobacter baumannii
  • multidrug resistant
  • escherichia coli
  • drug resistant
  • klebsiella pneumoniae
  • genetic diversity
  • crispr cas
  • single cell
  • cystic fibrosis
  • circulating tumor cells