Detection of Spinal Muscular Atrophy Using a Duplexed Real-Time PCR Approach With Locked Nucleic Acid-Modified Primers.

Jianyan Pan Chunhua Zhang Yanling Teng Sijing Zeng Siyi Chen Desheng Liang Zhuo Li Lingqian Wu

Published in: Annals of laboratory medicine (2020)

We have developed a novel, specific SMN1 detection approach utilizing real-time PCR with LNA-modified primers, which could be applied to both prenatal carrier and newborn screening.

Keyphrases

real time pcr
nucleic acid
label free