Interactions of SNPs in Folate Metabolism Related Genes on Prostate Cancer Aggressiveness in European Americans and African Americans.

Hui-Yi LinSusan E SteckIndrani SarkarElizabeth T H FonthamAlan DiekmanLora J RogersCalvin T RatliffJeannette T BensenJames L MohlerL Joseph Su

Published in: Cancers (2023)

These SNP-SNP interactions in the folate metabolism-related genes have a larger impact than SNP individual effects on tumor aggressiveness for EA and AA PCa patients. These findings can provide valuable information for potential biological mechanisms of PCa aggressiveness.

Keyphrases

genome wide
prostate cancer
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
dna methylation
radical prostatectomy
prognostic factors
genetic diversity
healthcare
climate change
social media