The role of alanine glyoxylate transaminase-2 (agxt2) in β-alanine and carnosine metabolism of healthy mice and humans.

Jan StautemasNatalia JarzebskaZhou Xiang ShanLaura Blancquaert Inge EveraertSarah de JagerSiegrid De BaereArne HautekietAnneke VolkaertFilip B D LefevereJens Martens-Lobenhoffer Stephanie M Bode-BögerChang Keun KimJames Leiper Norbert Weiss Siska Croubels Roman N Rodionov Wim Derave

Published in: European journal of applied physiology (2020)

The data suggest that in vivo, β-alanine is a substrate of AGXT2; however, its importance in the metabolism of β-alanine and histidine-containing dipeptides seems small.

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