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X chromosome aneuploidies and schizophrenia: association analysis and phenotypic characterization.

Itaru KushimaBranko AleksicHiroki KimuraMasahiro NakatochiTzuyao LoKyung Sue HongMakoto AraiRyota HashimotoShusuke NumataYasunobu OkamuraTaku ObaraToshiya InadaNorio Ozaki
Published in: Psychiatry and clinical neurosciences (2022)
These findings indicate that both 47, XXY and 47, XXX are significantly associated with risk for SCZ. Patients with SCZ with 47, XXY may be characterized by treatment-resistance and manic symptoms.
Keyphrases
  • bipolar disorder
  • copy number
  • gene expression
  • sleep quality
  • physical activity
  • depressive symptoms