Controllable signal molecule release from Au NP-gated MSNs for photocathodic detection of ultralow level AβO.

Xuechen ZhangJinling ZhangYao GaoJianyue YanWenbo Song

Published in: Chemical communications (Cambridge, England) (2022)

By integrating a target-responsive MSN-based controlled release system with a sensitization-SPR co-enhanced thionine/MoS 2 QDs/Cu NWs photocathode, a highly sensitive split-type PEC aptasensing platform for AβO detection in blood is constructed. Ultralow detection limit (2.1 fM) and high selectivity show great potential in early AD diagnosis.

Keyphrases

loop mediated isothermal amplification
label free
real time pcr
wastewater treatment
sensitive detection
high throughput
high resolution
mass spectrometry
single cell
aqueous solution