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Chronic Serotonergic Overstimulation Mimicking Panic Attacks in a Patient with Parkinson's Disease Receiving Additional Antidepressant Treatment with Moclobemide.

Marc PraetnerTimo SchieleLukas WerleJanina KufferSandra NischwitzMartin E KeckStefan Kloiber
Published in: Case reports in psychiatry (2021)
The specific pharmacological regime in this case probably caused drug-drug interactions resulting in a plethora of psychovegetative symptoms. Likely due to the delayed onset of adverse effects, physicians had difficulties in determining the pharmacologically induced serotonin toxicity. This case report emphasizes the complexity of pharmacological treatments and the importance of drug-drug interaction awareness in the treatment of PD patients with complicating nonmotor dysfunctions such as depression.
Keyphrases
  • case report
  • drug induced
  • primary care
  • oxidative stress
  • depressive symptoms
  • combination therapy
  • bipolar disorder