Improvement effects of transplanting pancreatic islet that previously incubated with biomaterials on the diabetic nephropathy in STZ- diabetic rats.
Marzieh NematiZahra HosseinzadehFatemeh NematiFarhad KoohpeymaPublished in: BMC nephrology (2024)
Biomaterials treated islets transplanting could improve diabetic nephropathy. Improvement of oxidative stress followed by controlling glucose level, and effects of growth factors presenting in biomaterials can be considered as capable underlying mechanism of ameliorating inflammatory, necrotic and fibrotic tissue volume.
Keyphrases
- diabetic nephropathy
- diabetic rats
- oxidative stress
- tissue engineering
- bone regeneration
- ischemia reperfusion injury
- dna damage
- induced apoptosis
- idiopathic pulmonary fibrosis
- systemic sclerosis
- blood glucose
- case report
- metabolic syndrome
- skeletal muscle
- insulin resistance
- heat shock
- newly diagnosed
- signaling pathway
- heat stress