How safe is off-label use of imiquimod in oral lesions?
Ana Luisa AmaralBashir Abdulgader LwaleedJerry Elmer BouquotSérgio Araújo AndradePublished in: Evidence-based dentistry (2024)
The study elucidated the off-label use of imiquimod in oral pathologies, whether potentially malignant, cancerous, autoimmune, or associated with HPV infection. However, it was observed that further research is warranted for the development of a specific formulation for the oral mucosa, ensuring the drug's sustained presence at its active site of action without interference from saliva and minimizing potential side effects.