Impact of contemporary regimens on the outcomes and toxicity of primary CNS lymphoma: a single-center retrospective analysis of 73 patients.

Nadav SaridFelix BoksteinDeborah T BlumenthalAhuva Weiss-MeilikLili GibsteinIrit AviviChava PerryRon Ram

Published in: Journal of neuro-oncology (2020)

Contemporary HD MTX-based combination therapies suggestively improved the outcomes for PCNSL, but at a cost of increased incidence of toxicity. Patients who achieve an interim PR status are at a high risk for treatment failure.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
oxidative stress
chronic kidney disease
prognostic factors
peritoneal dialysis
diffuse large b cell lymphoma
patient reported outcomes
combination therapy