Enhanced IgA coating of bacteria in women with Lactobacillus crispatus-dominated vaginal microbiota.

Annelot C BreedveldHeleen J SchusterRobin van HoudtRebecca C PainterReina E MebiusCharlotte van der VeerSylvia M BruistenPaul H M SavelkoulMarjolein van Egmond

Published in: Microbiome (2022)

In conclusion, L. crispatus-dominated vaginal microbiota have higher levels of bacterial IgA coating compared to non-L. crispatus-dominated vaginal microbiota. Similar to its regulating function in the intestinal tract, we hypothesize that IgA is involved in maintaining L. crispatus-dominated microbiota in the female genital tract. This may play a role in L. crispatus-associated health benefits. Video abstract.

Keyphrases

public health
mental health
climate change
risk assessment
health promotion