Dynamic changes of soluble ST2 levels predicted fatality and were involved in coagulopathy in dengue fever in the elderly.

Chih-Cheng HsiehMing-Yuan HongTzong-Shiann HoChing-Chuan LiuGuey-Chuen PerngChia-Chang Chuang

Published in: PLoS neglected tropical diseases (2019)

Serum ST2 levels increased in the elderly (≥ 65 years of age) with DENV infection. The changes in serum sST2 levels might be a critical indicator of DENV infection severity for the elderly; sST2 is an important modulator of coagulopathy in severe DENV infections.

Keyphrases

dengue virus
middle aged
community dwelling
zika virus
aedes aegypti
drug induced