l-Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs.
Eric B McClellanZhengming WangKurt H AlbertineMark R KaplowitzYongmei ZhangCandice D FikePublished in: Pediatric pulmonology (2020)
Alterations in the structure of the pulmonary circulation in CH piglets by l-citrulline are unlikely to be mediated by overall VEGF signaling. Nonetheless, l-citrulline- induced structural changes should reduce PVR and thereby contribute to the amelioration of CH-induced PH.