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Anti-inflammatory Effect of Predimenol, A Bioactive Extract from Phaleria macrocarpa, through the Suppression of NF-κB and COX-2.

Yurike YulianaOlivia M TandrasasmitaRaymond R Tjandrawinata
Published in: Recent advances in inflammation & allergy drug discovery (2022)
Predimenol exhibits anti-inflammatory activities through NF-kB inactivation-mediated COX-2 suppression, which may suggest that predimenol is a potential analgesic and anti-inflammatory agent.
Keyphrases
  • anti inflammatory
  • signaling pathway
  • lps induced
  • pi k akt
  • nuclear factor
  • inflammatory response
  • immune response
  • spinal cord
  • cell proliferation
  • spinal cord injury
  • risk assessment
  • neuropathic pain