Increased carotid intima-media thickness in patients with radiographic axial spondyloarthritis compared to controls and associations with markers of inflammation.
Lucy LawPer LindqvistPer LivUrban HellmanKristina LejonMats GeijerStefan SöderbergHelena Forsblad-d'EliaPublished in: Clinical rheumatology (2024)
Patients with r-axSpA had significantly increased cIMT compared to controls. In male patients, higher WBC and monocyte count were associated with an increase in cIMT suggesting the role of inflammation in the development of atherosclerosis. Key Points •Carotid intima-media thickness was increased in patients with radiographic axial spondyloarthritis compared to controls. •White blood cell and monocyte counts were associated with carotid intima-media thickness in male patients with radiographic axial spondyloarthritis.
Keyphrases
- ankylosing spondylitis
- disease activity
- optical coherence tomography
- peripheral blood
- oxidative stress
- end stage renal disease
- dendritic cells
- cardiovascular risk factors
- ejection fraction
- newly diagnosed
- chronic kidney disease
- endothelial cells
- cardiovascular disease
- rheumatoid arthritis
- systemic lupus erythematosus
- peritoneal dialysis
- cell therapy
- type diabetes
- mesenchymal stem cells
- patient reported outcomes
- patient reported