Autologous non-invasively derived stem cells mitochondria transfer shows therapeutic advantages in human embryo quality rescue.
Zhixin JiangCheng ShiHongjing HanMin FuHonglan ZhuTingting HanJia FeiYining HuangZhiping JinJianan HeYanbin WangXi ChenHuan ShenPublished in: Biological research (2023)
Autologous non-invasively derived USC mitochondria transfer may be an effective strategy to improve embryonic development and metabolism, especially in infertile females with advanced age or repeated pregnancy failure. It provides evidence and possibility for the autologous treatment of infertile females without invasive and ethical concerns.
Keyphrases
- cell therapy
- stem cells
- bone marrow
- platelet rich plasma
- endothelial cells
- cell death
- polycystic ovary syndrome
- reactive oxygen species
- endoplasmic reticulum
- preterm birth
- type diabetes
- induced pluripotent stem cells
- quality improvement
- decision making
- metabolic syndrome
- adipose tissue
- insulin resistance
- smoking cessation