An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation.
Vaibhav PatilRaghvendra BoharaCarla WinterMichelle KilcoyneSiobhan McMahonAbhay PanditPublished in: CNS neuroscience & therapeutics (2022)
The present study is the first functional investigation of glycosylation modulation in a mixed glial culture model, which elucidates the role of the glycome in neuroinflammation in progression and identified potential therapeutic targets for future glyco therapeutics in neuroinflammation.
Keyphrases
- oxidative stress
- traumatic brain injury
- lipopolysaccharide induced
- lps induced
- neuropathic pain
- liver failure
- cognitive impairment
- cerebral ischemia
- drug induced
- small molecule
- respiratory failure
- inflammatory response
- current status
- human health
- brain injury
- spinal cord injury
- acute respiratory distress syndrome
- mechanical ventilation