Safety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions.
Aaron Rodriguez CalienesMilagros Galecio-CastilloMudassir FarooquiAmeer E HassanMouhammad A JumaaAfshin A DivaniMarc RiboMichael G AbrahamNils H PetersenJohanna T FifiWaldo R GuerreroAmer M MalikJames E SieglerThanh N NguyenAlbert J YooGuillermo LinaresNazli JanjuaDarko Quispe-OrozcoWondwossen G TekleHisham AlhajalaAsad IkramFederica RizzoAbid Y QureshiLiza BegunovaStavrous MatsoukasNicholas F VigilanteSergio Salazar-MarioniMohamad AbdalKaderWeston GordonJazba SoomroCharoskhon TurabovaJuan Vivanco-SuarezMaxim MokinDileep R YavagalTudor G JovinSunil A ShethSantiago Ortega GutierrezPublished in: Stroke (2023)
Our study showed that the combination of IVT with MT for tandem lesions did not increase the overall risk of sICH, parenchymal hematoma type 2, or overall hemorrhagic transformation independently of the cervical revascularization technique used. However, intraprocedural intravenous antiplatelet therapy during acute stent implantation might be associated with an increased risk of sICH in patients who received IVT before MT. Importantly, IVT+MT treatment was associated with a higher rate of favorable functional outcomes at 90 days.
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