Testing for a Sweet Spot in Randomized Trials.

Donald A RedelmeierDeva ThiruchelvamRobert J Tibshirani

Published in: Medical decision making : an international journal of the Society for Medical Decision Making (2021)

Systematic methods are available beyond simple stratification for identifying a sweet spot according to disease severity. The approach can assess whether some patients experience more relative benefit than other patients in a randomized trial.[Box: see text].

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
smoking cessation