Therapeutic potency of heat-shock protein-90 pharmacological inhibitors in the treatment of gastrointestinal cancer, current status and perspectives.
Nadia BoroumandHossein SaghiAmir AvanAmirhossein BahreyniMikhail RyzhikovMajid KhazaeiSeyed Mahdi HassanianPublished in: The Journal of pharmacy and pharmacology (2017)
We have presented different antitumour mechanisms of HSP90 inhibitors in cancer treatment. Suppression of HSP90 signalling via specific and novel pharmacological inhibitors is a potentially novel therapeutic approach for patients with GI cancer for a better understanding and hence a better management of this disease.