Alginate-based matrix tablets for drug delivery.
Natalia VeronicaPaul Wan Sia HengCeline Valeria LiewPublished in: Expert opinion on drug delivery (2022)
Alginate-based matrix tablets provide an alternative method for sustaining drug release. Being a nature-derived polymer, batch consistency and stability of the alginate raise some concerns about employing alginate in formulations. Furthermore, the alginate gel properties can be affected by formulation component, pH of the dissolution environment and the tablet matrix micro-environment pH. Conscientious efforts are pivotal to addressing these formulation challenges to increase the utilization of alginate in oral solid dosage forms.