Differential effect of the ultra-low dose and standard estrogen plus dydrogesterone therapy on thrombin generation and fibrinolysis in postmenopausal women.

Magdalena PirógRobert JachOlga Kacalska-Janssen

Published in: Acta obstetricia et gynecologica Scandinavica (2017)

Contrary to the standard estrogen plus dydrogesterone treatment, ultra-low dose HT revealed positive effects on hemostasis by intensifying fibrinolysis through a decrease in both PAI-1 activity and antigen levels, and with no impact on thrombin generation.

Keyphrases

low dose
postmenopausal women
bone mineral density
high dose
estrogen receptor
high resolution
replacement therapy