Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection.

Anan HuangYue LiuXin QiShang ChenHaoyan HuangJun ZhangZhibo HanZhong-Chao HanZongjin Li

Published in: Stem cell research & therapy (2022)

This study identifies intravenously transplanted MSCs, as an endocrine reservoir, to secrete cardioprotective EVs into blood continuously and gradually to confer the trans-organ communication that relieves Dox-induced cardiotoxicity.

Keyphrases

mesenchymal stem cells
bone marrow
high glucose
diabetic rats
genome wide
water quality
oxidative stress