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BRD2-specific inhibitor, BBC0403, inhibits the progression of osteoarthritis pathogenesis in osteoarthritis-induced C57BL/6 male mice.

Hyemi LeeJiho NamHahyeong JangYoung-Sik ParkMin-Hee SonIn-Hyun LeeSeong-Il EyunJae-Hyun YangJimin JeonSiyoung Yang
Published in: British journal of pharmacology (2024)
This study demonstrated that BBC0403 is a novel BRD2-specific inhibitor and a potential i.a.-injectable therapeutic agent to treat OA.
Keyphrases
  • knee osteoarthritis
  • rheumatoid arthritis
  • high glucose
  • diabetic rats
  • drug induced
  • hyaluronic acid
  • risk assessment
  • tissue engineering