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DNA polymerase epsilon is required for heterochromatin maintenance in Arabidopsis.

Pierre BourguetLeticia López-GonzálezÁngeles Gómez-ZambranoThierry PélissierAmy HeskethMagdalena E PotokMarie-Noëlle Pouch-PélissierMagali PerezOlivier Da InesDavid LatrasseCharles I WhiteSteven E JacobsenMoussa BenhamedOlivier Mathieu
Published in: Genome biology (2020)
These results indicate that POL2A is critical to heterochromatin structure and function, and that unhindered replisome progression is required for the faithful propagation of DNA methylation throughout the cell cycle.
Keyphrases
  • cell cycle
  • dna methylation
  • cell proliferation
  • circulating tumor
  • transcription factor
  • genome wide
  • cell free
  • gene expression
  • single molecule
  • nucleic acid
  • copy number
  • plant growth