Achilles Tendons Display Region-Specific Transcriptomic Signatures Associated With Distinct Mechanical Properties.

Nathaniel P DisserAlexander N PiacentiniAndrea J De MicheliMartin M SchonkVincent J H YaoXiang-Hua DengDavid J OliverScott A Rodeo

Published in: The American journal of sports medicine (2022)

These findings improve our understanding of the underlying biological heterogeneity of tendon tissue and will help inform the future targeted use of regenerative medicine and tissue engineering strategies for patients with tendon disorders.

Keyphrases

tissue engineering
single cell
anterior cruciate ligament reconstruction
rotator cuff
rna seq
cancer therapy
genome wide
gene expression
dna methylation