Psoriasiform dermatitis during dupilumab treatment for moderate-to-severe atopic dermatitis in children.
Jennifer J ParkerJeffrey L SugarmanNanette B SilverbergMercedes Elena GonzalezMichele L RamienJoyce M C TengAmy S PallerPublished in: Pediatric dermatology (2021)
Although unusual, psoriasiform lesions can appear during effective treatment with dupilumab for atopic dermatitis, potentially reflecting a shift toward cutaneous IL-23/TH 17 pathway activation with dupilumab-induced suppression of type 2 immunity.