Dose-dense neoadjuvant chemotherapy before radical surgery in cervical cancer: a retrospective cohort study and systematic literature review.
Giuseppe CarusoSimone BruniMariateresa LapresaLuigi A De VitisGabriella ParmaValentina MinicucciIlaria BetellaGabriella SchivardiFedro PeccatoriRoberta LazzariWilliam A ClibyGiovanni Damiano AlettiVanna ZanagnoloAngelo MaggioniNicoletta ColomboFrancesco MultinuPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
Dose-dense neoadjuvant chemotherapy before radical surgery could be a valid strategy to avoid radiotherapy in stage IB1-IIA2 cervical cancer, especially in young patients desiring to preserve overall quality of life. Prospective research is warranted to provide robust, high-quality evidence.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- minimally invasive
- lymph node
- sentinel lymph node
- coronary artery bypass
- rectal cancer
- end stage renal disease
- squamous cell carcinoma
- radiation therapy
- newly diagnosed
- ejection fraction
- early stage
- peritoneal dialysis
- prognostic factors
- radiation induced
- coronary artery disease
- acute coronary syndrome
- middle aged