A Retrospective Study of Factors Contributing to the Performance of an Interferon-Gamma Release Assay Blood Test for Tuberculosis Infection.

Published in: Clinical chemistry (2024)

These findings highlight the influence of clinical context and patient hematologic profiles on QFT-Plus results. To minimise neglected latent TB infections due to false-negative QFT-Plus results, serial retesting is advisable in patients with severe lymphopenia or neutrophilia, particularly when the mitogen response is <10 IU/mL.

Keyphrases

mycobacterium tuberculosis
protein kinase
case report
high throughput
dendritic cells
early onset
nuclear factor
hiv aids
emergency department
adverse drug
immune response
inflammatory response
drug induced
hiv infected