Birth and coming of age of islet autoantibodies.

Published in: Clinical and experimental immunology (2019)

This review takes the reader through 45 years of islet autoantibody research, from the discovery of islet-cell antibodies in 1974 to today's population-based screening for presymptomatic early-stage type 1 diabetes. The review emphasizes the current practical value of, and factors to be considered in, the measurement of islet autoantibodies.

Keyphrases

early stage
type diabetes
systemic lupus erythematosus
small molecule
single cell
cardiovascular disease
cell therapy
stem cells
high throughput
insulin resistance
gestational age
skeletal muscle