Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification.
Ruth F DubinRajat DeoYue RenJianqiao WangAlexander R PicoJosyf C MychaleckyiJulia KozlitinaVictoria ArthurHongzhe LeeAmil ShahHarold FeldmanNisha BansalLeila ZelnickPanduranga RaoNidhi SukulDominic S RajRupal MehtaSylvia E RosasZeenat BhatMatthew R WeirJiang HeJing ChenMayank KansalPaul L KimmelVasan S RamachandranSushrut S WaikarMark R SegalPeter Ganznull nullPublished in: European heart journal (2024)
Large-scale proteomics reveal novel circulating protein biomarkers and potential mediators of HF in CKD. Proteomic risk models improve upon the PCP-HF risk score in this population.
Keyphrases
- label free
- heart failure
- acute heart failure
- mass spectrometry
- chronic kidney disease
- cardiovascular disease
- genome wide
- left ventricular
- protein protein
- atrial fibrillation
- human health
- binding protein
- cardiac resynchronization therapy
- amino acid
- gene expression
- risk assessment
- type diabetes
- small molecule
- dna methylation