Pitfalls in genetic testing: a case of a SNP in primer-annealing region leading to allele dropout in BRCA1.

Felipe Carneiro SilvaGiovana Tardin TorrezanRafael Canfield BrianeseRaquel StabelliniGiovana Tardin Torrezan

Published in: Molecular genetics & genomic medicine (2017)

Assuming that this problem can also occur in any PCR-based method that are widely used in diagnostic settings, the clinical report presented here draws attention for one of the limitations of genetic testing in general, for which medical and laboratory communities need to be aware.

Keyphrases

healthcare
genome wide
working memory
dna methylation
real time pcr