Surgical site infection caused by Aeromonas hydrophila presenting as necrotizing soft tissue infection after esophagectomy.
Osamu YamasakiEizo TakahashiKazuyo NodaNobuhiko KanayaShunsuke TanabeYasuhiro ShirakawaShin MorizanePublished in: The Journal of dermatology (2020)
Several virulence factors of Aeromonas such as hemolysin, proteases and lipases have been characterized. The relationship between these virulence factors and disease remains unclear. A 71-year-old man underwent thoracoscopic esophagectomy, lymph node dissection and Roux-en-Y reconstruction for esophageal cancer. On postoperative day 1, redness around the wound on the thoracic abdominal wall gradually enlarged and necrosis became apparent with septic shock. Necrotizing soft tissue infection was suspected and emergency surgical debridement was performed. Blood and wound cultures were positive for Aeromonas hydrophila. The strain was found to have hemolytic activity, proteolytic activity and extremely high elastolytic activity. In addition, the strain actively produced elastolytic metalloprotease, which may contribute to extensive tissue necrosis.
Keyphrases
- surgical site infection
- soft tissue
- septic shock
- escherichia coli
- robot assisted
- pseudomonas aeruginosa
- staphylococcus aureus
- public health
- healthcare
- emergency department
- antimicrobial resistance
- biofilm formation
- spinal cord
- rectal cancer
- squamous cell carcinoma
- spinal cord injury
- pulmonary embolism
- magnetic resonance imaging
- gastric bypass
- magnetic resonance
- weight loss
- early stage
- neoadjuvant chemotherapy
- obese patients