Genomic mutation profiling using liquid biopsy in Korean patients with prostate cancer: Circulating tumor DNA mutation predicts the development of castration resistance.
Jiwoong YuEun Hae ChoJoongwon ChoiJoung Eun LimJunnam LeeMinyong KangHyun Hwan SungByung Chang JeongSeong Il SeoSeong Soo JeonHyun Moo LeeHwang Gyun JeonPublished in: Investigative and clinical urology (2022)
Korean patients with prostate cancer showed a relatively low germline mutation rate compared to other ethnicities. The ctDNA mutations detected by liquid biopsy can predict the development of castration resistance in patients with mHSPC.