Switching to testicular sperm after a previous ICSI failure with ejaculated sperm significantly improves blastocyst quality without increasing aneuploidy risk.

Irene HervásMaria Gil JuliaRocío Rivera-EgeaAna Navarro-GomezlechonLaura MossettiNicolás Garrido

Published in: Journal of assisted reproduction and genetics (2022)

Switching to testicular sperm for ICSI yielded better-quality blastocysts without affecting the chromosomal load of the embryos in non-azoospermic couples with a previous unsuccessful ICSI using ejaculated sperm. This strategy is a good option for couples seeking a livebirth who do not want to use donor sperm.

Keyphrases

pregnancy outcomes
germ cell
quality improvement
pregnant women
gene expression
copy number
intimate partner violence