Development and validation of a point-of-care breath test for octane detection.

Laura A HagensAlwin R M VerschuerenAriana LammersNanon F L HeijnenMarry R SmitTamara M E NijsenInge GevenMarcus J SchultzDennis C J J BergmansRonny M SchnabelLieuwe D J Bos

Published in: The Analyst (2021)

This is the first study to show that a POC breath test can rapidly and reliably detect octane, with excellent repeatability, at clinically relevant levels of low ppb in exhaled breath of ventilated ICU patients. This opens possibilities for targeted exhaled breath analysis to be used as a bedside test and makes it a potential diagnostic tool for the early detection of ARDS.

Keyphrases

intensive care unit
acute respiratory distress syndrome
end stage renal disease
newly diagnosed
ejection fraction
mechanical ventilation
prognostic factors
extracorporeal membrane oxygenation
peritoneal dialysis
risk assessment
patient reported outcomes
quantum dots