Sp1-regulated transcription of RasGRP1 promotes hepatocellular carcinoma (HCC) proliferation.
Xinran ZhangHao ZhuangFeng HanXiaowen ShaoYun LiuXuda MaZun WangZhaoyan QiangYongmei LiPublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
RasGRP1 is upregulated in HCC and promotes HCC cell proliferation. Thus, RasGRP1 may be a novel therapeutic target for HCC.