The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization.

Huadan XuDong LiJiaoyan MaYuanxin ZhaoLong XuRui TianYanan LiuLiankun Sun Jing Su

Published in: Cancer biology & medicine (2021)

These results clarify the interaction between the IL-33/ST2 pathway and macrophage polarization, and may pave the way to the development of new cancer immunotherapies targeting the IL-33/ST2 axis.

Keyphrases

papillary thyroid
squamous cell carcinoma
squamous cell
drug delivery
cancer therapy
childhood cancer