Evaluation of Xpert Carba-R Assay v.2 to Detect Carbapenemase Genes in Two Hospitals in Korea.
Jung-Hyun ByunYoung Ah KimMilee KimBomi KimJun Yong ChoiYoon Soo ParkDongeun YongPublished in: Annals of laboratory medicine (2020)
Carba-R v.2 is a rapid and sensitive method for detecting carbapenemase-encoding genes compared with culture-based conventional PCR. Most of our discrepant results were non-KPC genes. Thus, the clinical significance of the non-KPC positive cases detected by Carba-R v.2 should be investigated. This assay would be useful for deciding whether to isolate pre-exposed patients in hospital settings, based on the high specificity and NPV.
Keyphrases
- klebsiella pneumoniae
- genome wide
- end stage renal disease
- multidrug resistant
- healthcare
- bioinformatics analysis
- escherichia coli
- genome wide identification
- high throughput
- newly diagnosed
- chronic kidney disease
- ejection fraction
- acinetobacter baumannii
- prognostic factors
- genome wide analysis
- drug resistant
- dna methylation
- emergency department
- gene expression
- atomic force microscopy
- high resolution
- structural basis