Phenotypical and Functional Characterization of Neutrophils in Two Pyrin-Associated Auto-inflammatory Diseases.

Bert Malengier-DevliesMieke MetzemaekersMieke GouwyErika Van NieuwenhoveAlbrecht BetrainsMaaike CockxLotte VanbrabantNoëmie PörtnerJurgen VercauterenLien De SomerSofie StruyfSteven VanderschuerenEllen De LangheMieke GouwyPatrick MatthysCarine Wouters

Published in: Journal of clinical immunology (2021)

Neutrophils from patients with FMF and PAAND, carrying different mutations in the MEFV gene, share a pro-inflammatory phenotype yet demonstrate diverse features, underscoring the distinction between both diseases.

Keyphrases

oxidative stress
genome wide
copy number
gene expression
genome wide identification