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White Matter Plasticity Underpins Cognitive Gains after Multidomain Adaptive Computerized Cognitive Training.

Xiangwei DaiSihan LiuYumeng LiShijie LongXin LiChuansheng ChenCaishui YangJunying ZhangZhuo Rachel HanHe LiJun WangZhanjun Zhang
Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Our findings suggest that conducting multidomain adaptive CCT is an effective and feasible method to counteract cognitive decline in older adults, with WM neuroplasticity underpinning cognitive improvements. This study contributes to the understanding of the neural basis for the beneficial effect of CCT for older adults.
Keyphrases
  • cognitive decline
  • white matter
  • mild cognitive impairment
  • physical activity
  • electronic health record