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Natural language processing in text mining for structural modeling of protein complexes.

Varsha D BadalPetras J KundrotasIlya A Vakser
Published in: BMC bioinformatics (2018)
The basic TM procedure for extracting protein-protein binding site residues from the PubMed abstracts was significantly advanced by the deep parsing (NLP techniques for contextual analysis) in purging of the initial pool of the extracted residues. Benchmarking showed a substantial increase of the docking success rate based on the constraints generated by the advanced TM with NLP.
Keyphrases
  • protein protein
  • small molecule
  • autism spectrum disorder
  • minimally invasive
  • molecular dynamics simulations