Ethnicity Associated Microbial and Metabonomic Profiling in Newly Diagnosed Ulcerative Colitis.

Ravi MisraMagali SarafianAlexandros PechlivanisNik DingJesus Miguens-BlancoJulie McDonaldElaine HolmesJulian MarchesiNaila Arebi

Published in: Clinical and experimental gastroenterology (2022)

Ethnic-related microbial metabolite associations were observed in South Asians with UC. This suggests a predisposition to UC may be influenced by environmental factors reflected in a distinct gene-environment interaction. The variations may serve as markers to identify risk factors for UC and modified to enhance therapeutic response.

Keyphrases

newly diagnosed
ulcerative colitis
microbial community
copy number
single cell
gene expression
genome wide identification
transcription factor
genome wide analysis