Urine NGAL and KIM-1: tubular injury markers in acute lymphoblastic leukemia survivors.

Eryk LatochKatarzyna KonończukKatarzyna Taranta-JanuszKatarzyna Muszyńska-RosłanEdyta SzymczakAnna WasilewskaMaryna Krawczuk-Rybak

Published in: Cancer chemotherapy and pharmacology (2020)

We demonstrated that ALL survivors have higher levels of urine NGAL, NGAL/cr. and uKIM-1/cr. ratio as compared to the control group. Further long-term follow-up studies are necessary to assess the significance of the NGAL and KIM-1 and their relationship to kidney damage after anticancer treatment in childhood.

Keyphrases

acute lymphoblastic leukemia
young adults
oxidative stress
early life
replacement therapy
high glucose
case control
smoking cessation