A new player in the biogenesis of lysosome-related organelles.

Published in: The Journal of cell biology (2024)

How are Rab GTPases regulated during lysosome-related organelle (LRO) biogenesis? Li et al. (https://doi.org/10.1083/jcb.202402016) identify LYSMD proteins as crucial activators of Rab32-family GTPases in LRO development, shedding light on the previously ambiguous mechanisms governing Rab functionality in this process.

Keyphrases

living cells
transcription factor
single molecule