Sex-specific effect of prenatal alcohol exposure on N-methyl-D-aspartate receptor function in orbitofrontal cortex pyramidal neurons of mice.

Valentina LicheriJayapriya ChandrasekaranClark W BirdC Fernando ValenzuelaJonathan L Brigman

Published in: Alcoholism, clinical and experimental research (2021)

These findings suggest that low-to-moderate PAE modulates NMDAR function in pyramidal neurons in a sex-specific manner, although we did not find evidence that the effect is mediated by dysfunction of synaptic GluN2B subunit-containing NMDARs.

Keyphrases

spinal cord
pregnant women
oxidative stress
high intensity
functional connectivity
high fat diet induced
metabolic syndrome
alcohol consumption
adipose tissue
protein kinase