Chemotherapy-Induced Collagen IV Drives Cancer Cell Motility through Activation of Src and Focal Adhesion Kinase.

Jackson P Fatherree Justinne R Guarin Rachel A McGinnStephen P NaberMadeleine J Oudin

Published in: Cancer research (2022)

Cytotoxic chemotherapy induces significant changes in the composition of tumor ECM, inducing a more invasive and aggressive phenotype in residual tumor cells following chemotherapy.

Keyphrases

chemotherapy induced
tyrosine kinase
biofilm formation
locally advanced
squamous cell carcinoma
protein kinase
escherichia coli
rectal cancer
cystic fibrosis